发明名称 |
CRYSTALLINE STRUCTURE OF THE CC2-LZ DOMAIN OF NEMO |
摘要 |
The invention relates to a crystal of the CC2-LZ domain of the NEMO protein, in which the three-dimensional structure has been determined by X-ray diffraction at a resolution of about 3.25 Angstrom. The invention also relates to methods for the crystallisation of the CC2-LZ domain. The CC2-LZ crystals and the information derived from the crystalline structures thereof are used for identifying and designing compounds interacting with CC2-LZ. |
申请公布号 |
EA020189(B1) |
申请公布日期 |
2014.09.30 |
申请号 |
EA20100001228 |
申请日期 |
2009.02.05 |
申请人 |
LES LABORATOIRES SERVIER;INSTITUT PASTEUR |
发明人 |
AGOU FABRICE;CHIARAVALLI JEANNE;DUQUERROY STEPHANE;FONTAN ELISABETH;GRUBISHA OLIVERA;KAMINSKA MONIKA DOROTA;VERON MICHEL;CORDIER FLORENCE |
分类号 |
C07K14/47;A61K38/17;C12N15/09;G06F17/50 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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