| 摘要 |
PROBLEM TO BE SOLVED: To provide a TRK kinase inhibitor.SOLUTION: A compound of the formula I is a Trk kinase inhibitor and useful for treatments for diseases which can be treated by Trk kinase inhibitors, and R, R, R, R, X, Y and n in the formula have meanings described in the specification. There is also provided a method for treating pain, cancer, inflammation, neurodegenerative disease or Trypanosoma cruzi infection in mammals including administering a therapeutically effective amount of the compound of the formula I according to any one of claims 1 to 32 or a pharmaceutically acceptable salt thereof to the mammals. |
