PROCESS FOR MAXIMIZING BIOMASS GROWTH AND BUTANOL YIELD BY FEEDBACK CONTROL
摘要
<p>Provided herein are methods of maximizing biomass production and butanol (e.g., isobutanol) yield during fermentation of recombinant microorganisms. Biomass production during a biomass growth phase and/or butanol production during a butanol production phase can be maximized by adjusting a manipulated variable, such as feed rate, in response to a controlled variable, such as respiratory quotient (RQ).</p>