发明名称 NUCLEIC ACID MOLECULE FOR INHIBITING ACTIVITY OF RNAI MOLECULE
摘要 The purpose of the present invention is to develop and provide a nucleic acid molecule that can specifically and efficiently inhibit the activity of a target RNAi molecule and can be produced safely at a low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target RNAi molecule. The nucleic acid molecule comprises a single-stranded nucleic acid moiety that contains one unmodified DNA region composed of a nucleotide sequence completely or sufficiently complementary to a nucleotide sequence of a functional strand having the activity in the target RNAi molecule and a double-stranded nucleic acid moiety to be linked to at least one of the 5'-end and the 3'-end of the single-stranded nucleic acid moiety.
申请公布号 EP2781598(A1) 申请公布日期 2014.09.24
申请号 EP20120850603 申请日期 2012.11.14
申请人 OSAKA CITY UNIVERSITY 发明人 TACHIBANA, AKIRA;TANABE, TOSHIZUMI
分类号 C12N15/113;A61K31/7105;A61K31/713;A61P35/00 主分类号 C12N15/113
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