发明名称 |
NUCLEIC ACID MOLECULE FOR INHIBITING ACTIVITY OF RNAI MOLECULE |
摘要 |
The purpose of the present invention is to develop and provide a nucleic acid molecule that can specifically and efficiently inhibit the activity of a target RNAi molecule and can be produced safely at a low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target RNAi molecule. The nucleic acid molecule comprises a single-stranded nucleic acid moiety that contains one unmodified DNA region composed of a nucleotide sequence completely or sufficiently complementary to a nucleotide sequence of a functional strand having the activity in the target RNAi molecule and a double-stranded nucleic acid moiety to be linked to at least one of the 5'-end and the 3'-end of the single-stranded nucleic acid moiety. |
申请公布号 |
EP2781598(A1) |
申请公布日期 |
2014.09.24 |
申请号 |
EP20120850603 |
申请日期 |
2012.11.14 |
申请人 |
OSAKA CITY UNIVERSITY |
发明人 |
TACHIBANA, AKIRA;TANABE, TOSHIZUMI |
分类号 |
C12N15/113;A61K31/7105;A61K31/713;A61P35/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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