发明名称 |
Dirección a la regulación de VEGF-B de transportadores de ácidos grasos para modular enfermedades humanas |
摘要 |
The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. In particular, the present invention concerns an oligonucleotide which inhibits VEGF-B expression for use in the treatment or prophylaxis of type II diabetes or metabolic syndrome wherein the oligonucleotide is selected from (a) an antisense oligonucleotide that inhibits VEGF-B transcription or translation or an expression vector which expresses such an oligonucleotide; or (b) a dsRNA that affects RNA interference or expresses such a dsRNA. |
申请公布号 |
ES2497641(T3) |
申请公布日期 |
2014.09.23 |
申请号 |
ES20120178894T |
申请日期 |
2007.05.17 |
申请人 |
THE LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
ERIKSSON, ULF |
分类号 |
A61K39/395;C07K16/00;C07K16/22;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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