发明名称 METHOD FOR PREDICTION OF STAGE OF MULTIPLE SCLEROSIS TAKING INTO ACCOUNT VALUES OF IMMUNOLOGICAL STATUS
摘要 FIELD: medicine.SUBSTANCE: stage of the clinical course of multiple sclerosis is determined with using a regression equation: The course of the clinical course PC=0.161681 - 0.209483*sex+0.0158676*age+0.0477443* lymphocytes+0.578018* CD3 - 0.259435* CD19 - 2.29788* CD4+1.37512* CD8+0.680127* CD16 - 1.50333* CD11b+0.244827*"??" - 0.124693*"?????"+1.19125* "?????" - 0.0408168*IgG - 0.0501667*IgA+0.379248*IgM, wherein females are marked with one, and males are marked with two; age is completed years at the moment of examination. If the coefficient does not exceed 1.52, then the patient is considered to be apparently healthy. If the coefficient falls within the range of 1.53 - 2.8 standard units, the stage of remittance is predicted. If the coefficient is 2.9 or more, the patient suffers the stage of the active clinical course of multiple sclerosis.EFFECT: using the given method enables predicting the clinical course of multiple sclerosis taking into account the values of the patient's immunological status with the following correction of the therapeutic approach.1 ex
申请公布号 RU2528882(C1) 申请公布日期 2014.09.20
申请号 RU20130108180 申请日期 2013.02.25
申请人 GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIYA VORONEZHSKAYA GOSUDARSTVENNAYA MEDITSINSKAYA AKADEMIYAIM. N.N. BURDENKO MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII;PELESHENKO ELENA IVANOVNA 394036, G. VORONEZH, UL. STUDENCHESKAYA, D. 10, GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIYA VORONEZHSKAYA GOSUDARSTVENNAYAMEDITSINSKAYA AKADEMIYA IM. N.N. BURDENKO MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII 发明人 LUTSKIJ MIKHAIL ALEKSANDROVICH;ZEMSKOV ANDREJ MIKHAJLOVICH
分类号 G01N33/49 主分类号 G01N33/49
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