[Problem] To provide a means that is capable of suppressing changes in resistance associated with the depth of discharge and improving discharge rate characteristics in a battery that is intended particularly for high output use (with an internal resistance as small as 10 m&OHgr;/Ah (SOC 50%) or less) among large-size non-aqueous electrolyte secondary batteries capable of being used for driving electric vehicles, for example. [Solution] This non-aqueous electrolyte secondary battery comprises a power-generating element including: a positive electrode in which a positive-electrode active material layer including a positive-electrode active material is formed on the surface of a positive-electrode charge collector; a negative electrode in which a negative-electrode active material layer including a negative-electrode active material is formed on the surface of a negative-electrode charge collector; and a separator. In this secondary battery: the positive-electrode active material includes a spinel-type manganese positive-electrode active material and a lithium-nickel complex oxide; the rate of mixture of said lithium-nickel complex oxide to 100 wt% of said positive-electrode active material is 30 wt% or greater; and the internal resistance is 10 m&OHgr;/Ah or less (SOC 50%).