摘要 |
Disclosed are compounds of Formula (IIa), wherein R1, R2, R3A, R3B, R3C, R3D, R3E, and R4 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (IIa). |
申请人 |
ABBVIE INC. |
发明人 |
TONG, YUNSONG;BRUNCKO, MILAN;CLARK, RICHARD F.;CURTIN, MICHAEL L.;FLORJANCIC, ALAN S.;FREY, ROBIN R.;GONG, JIANCHUN;HANSEN, TODD M.;JI, ZHIQIN;LAI, CHUNQIU;MASTRACCHIO, ANTHONY;MICHAELIDES, MICHAEL;MIYASHIRO, JULIEM;RISI, ROBERTO M.;SONG, XIAOHONG;TAO, ZHI-FU;WOODS, KEITH W.;ZHU, GUIDONG;PENNING, THOMAS;SOUERS, ANDREW;GOSWAMI, RAJEEV;IQUTURI, OMPRAKASH REDDY;DABBEERU, MADHU BABU |