COMPOUNDS AND USES THEREOF IN THE TREATMENT/PREVENTION OF GRAM-NEGATIVE BACTERIAL INFECTIONS

摘要

The present disclosure relates to compounds of formula I in the treatment and/or prevention of a Gram-negative bacterial infection in a multicellular organism. The disclosure also relates to a pharmaceutical composition comprising said compound, a method of treatment and/or prevention of said infection comprising the administration of said compound, and the use of said compound for the manufacture of a medicament for treating and/or preventing said infection. The disclosure also relates to the modulation of the activity of a type three secretion system in a Gram-negative bacterium.