| 发明名称 |
TETRAHYDROISOQUINOLINE PRODUCTION METHOD |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide intermediates useful in producing tetrahydroisoquinolines, particularly 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine useful in the treatment of depression and other conditions.SOLUTION: Intermediates useful in producing tetrahydroisoquinolines are compounds represented by the specified formula (4R), where R1 is Br and H3CO.</p> |
| 申请公布号 |
JP2014169312(A) |
申请公布日期 |
2014.09.18 |
| 申请号 |
JP20140100580 |
申请日期 |
2014.05.14 |
| 申请人 |
BRISTOL MYERS SQUIBB CO;ALBANY MOLECULAR RES INC |
发明人 |
PAUL LOBBEN;ZHAO RULIN;WANG BEI;CHEN BANG-CHI;SHUANG LIU;HU MIN;YANG YUH-LIN ALLEN;MATTHEW ISHERWOOD;RASIDUL AMIN;CUI WENGE |
| 分类号 |
C07C225/06;C07C215/30;C07D217/04;C07F5/04 |
主分类号 |
C07C225/06 |
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