发明名称 METHOD FOR PRODUCING HUMAN CORNEAL EPITHELIUM SHEET
摘要 [Problem] To provide a method that is for producing a human corneal epithelium sheet for transplantation to corneal disease patients and that is for culturing, on an amnion substrate, human corneal epithelium-derived cells obtained by culturing human corneal epithelium cells. [Solution] A method for culturing human corneal epithelium cells using human mesenchymal stem cells as support cells, and a method for culturing human corneal epithelium cells using a culture medium to which has been added the combination of a ROCK inhibitor, a phosphodiesterase inhibitor, a MAP kinase inhibitor, and a TGF-&bgr; receptor antagonist.
申请公布号 WO2014142038(A1) 申请公布日期 2014.09.18
申请号 WO2014JP56078 申请日期 2014.03.09
申请人 JCR PHARMACEUTICALS CO., LTD.;KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION 发明人 IMAGAWA KIWAMU;MAEDA KENICHI;HOSODA YUKI;YOKOYAMA SHUICHI;OKUMURA NAOKI;KOIZUMI NORIKO;KINOSHITA SHIGERU
分类号 C12N5/071;A61L27/00 主分类号 C12N5/071
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