Systems and methods for intravenous drug management using immittance spectroscopy

摘要

Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition.

主权项

1. A method of determining the identity of a drug or drug formulation by recognizing a pattern of complex immittance from a library of known complex immittances, the method comprising:
receiving an initial dataset comprising complex immittance spectrographic information for an unknown liquid sample, the complex immittance spectrographic information taken from a plurality of different electrode pairs each at a plurality of different frequencies wherein each pair of electrodes had different surface properties arising from a different size, different shape, or different material relative to each other, and further wherein the complex immittance spectrographic information was recorded while the electrode pairs were in contact with the unknown liquid sample; using a processor to apply one or more pattern recognition techniques to compare the initial dataset to an identification space database comprising a plurality of identification datasets wherein the identification datasets comprise complex immittance data corresponding to known drug compositions to determine if the initial dataset matches an identification dataset from the identification space database within a threshold range; and reporting that the initial dataset does or does not match an identification dataset, and if the initial dataset does match an identification dataset within the threshold range, reporting which drug or drugs correspond to the identification dataset matched.