Photodamage mitigation compounds and systems

摘要

Compositions, devices, systems and methods for reducing and/or preventing photo-induced damage of one or more reactants in an illuminated analytical reaction by addition of one or more photoprotective compounds to the reaction mixture and allowing the reaction to proceed for a period that is less than a photo-induced damage threshold period.

主权项

1. A reaction mixture comprising a fluorescent or fluorogenic molecule, and a photoprotective agent, which photoprotective agent comprises a reducing functional group covalently bound to an oxidizing functional group wherein the photoprotective agent comprises a compound of a formula selected from the group consisting of:and a carboxylate salt thereof.