DEVICES, SYSTEMS, AND METHODS FOR ACOUSTICALLY -ENHANCED MAGNETOPHORESIS

摘要

Techniques to rapidly sort different types of cells from a blood sample are of interest in scientific research, the biotechnology industry and medicine. Fluorescence activated cell sorting (F ACS) is now a conventional and standard methodology, but it requires very expensive equipment and is inherently limited by the serial nature of single cell optical sorting. Existing alternative techniques such as centrifugation (using the variation of the density of different cells) and magnetophoresis (using micro/nano magnetic beads to label the cells of interest) have been widely used for the past few decades as parallel sorting techniques. Shortcomings of these common batchwise processes includes the following: they are typically non-continuous.