发明名称 METHOD FOR ASSESSING A LIVER OF A PATIENT HAVING A CHRONIC HEPATITIS B VIRUS INFECTION
摘要 The invention generally relates to method for assessing a liver of a patient having a chronic hepatitis B virus infection. In certain aspects, methods of the invention involve obtaining a sample from a patient having a chronic hepatitis B virus infection. An assay is conducted on the sample to determine a level of at least one biomarker regulated by Suz12/Znf198. The liver of the patient is then assessed based on the level of the at least one biomarker. Other aspects of the invention generally relate to reducing or eliminating replication of a hepatitis B virus, and preventing a chronic hepatitis B infection in a patient from progressing to a liver cancer.
申请公布号 US2014256735(A1) 申请公布日期 2014.09.11
申请号 US201414282033 申请日期 2014.05.20
申请人 PURDUE RESEARCH FOUNDATION 发明人 Andrisani Ourania
分类号 C12Q1/70 主分类号 C12Q1/70
代理机构 代理人
主权项 1. A method for assessing a liver of a patient having a chronic hepatitis B virus infection, the method comprising: obtaining a sample from a patient having a chronic hepatitis B virus infection; conducting an assay on the sample to determine a level of at least one biomarker regulated by Suz12/Znf198; and assessing a liver of the patient based on the level of the at least one biomarker.
地址 West Lafayette IN US