Peptide-Bound Gold Metal Nano-clusters as Cancer Cell Killing Agents

摘要

Peptide-bound gold metal nanocluser complexes are produced to induce cancer cell death by dramatically inhibiting TrxR activities of the cancer cells. Specificity is shown by selectively designing peptide sequences.

主权项

1. A method of inducing cancer cell death, comprising the steps of:
preparing a peptide and gold metal nano-cluster complex wherein said peptide contains a primary amino acid sequence targeting a type of cancer cells; and exposing said cancer cells to said peptide and gold metal nano-cluster complex molecules; and causing said cancer cell death at a concentration of said peptide and gold metal nano-cluster complex molecules that inhibit TrxR enzyme activities of said cancer cells.