发明名称 1-AZA-BICYCLO[3.3.1] NON-4-YL)-[5-(1H-INDOL-5-YL)-HETEROARYL]-AMINES AS CHOLINERGIC LIGANDS OF THE N-ACHR FOR THE TREATMENT OF PSYCHOTIC AND NEURODEGENERATIVE DISORDERS
摘要 The present invention related to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate, Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders.;
申请公布号 US2014256940(A1) 申请公布日期 2014.09.11
申请号 US201414285942 申请日期 2014.05.23
申请人 NOVARTIS AG 发明人 FREDERIKSEN Mathias;FEUERBACH Dominik;HURTH Konstanze;KOLLER Manuel;ROY Bernard Lucien
分类号 C07D471/08 主分类号 C07D471/08
代理机构 代理人
主权项
地址 BASEL CH