发明名称 |
MODULATORS OF MITOCHONDRIAL PROTEIN IMPORT |
摘要 |
The present invention provides compounds that modulate protein translocation in mitochondria, compositions thereof, and methods of identifying, making and using these. |
申请公布号 |
US2014249193(A1) |
申请公布日期 |
2014.09.04 |
申请号 |
US201214111265 |
申请日期 |
2012.04.12 |
申请人 |
Koehler Carla M.;Hasson Samuel A.;Miyata Kiyoko;Teitell Micheal A.;Dabir Deepa |
发明人 |
Koehler Carla M.;Hasson Samuel A.;Miyata Kiyoko;Teitell Micheal A.;Dabir Deepa |
分类号 |
A61K31/343;C12Q1/18;A61K31/404;A61K31/15;A61K31/4196 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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主权项 |
1. A specific inhibitor of mitochondrial protein translocation, which inhibitor modulates the assembly or function of mitochondria, wherein the inhibitor specifically targets the protein translocation pathway thereby modulating the assembly and function of the mitochondrion with respect to protein translocation and import. |
地址 |
Los Angeles CA US |