| 发明名称 |
2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYLOXY]INDOLE IN COMBINATION WITH ESTROGENS |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide pharmaceutical compositions that alleviate undesirable side effects of estrogen therapy and minimize the dose of estrogen, for alleviating symptoms of post-menopausal syndrome in women.SOLUTION: Provided are pharmaceutical compositions containing one or more estrogens, 2-phenyl-1-[4-(2-aminoethoxy)benzyl]indole compounds which are useful as estrogenic agents, as well as compounds represented by the general formula (I) or (II), and methods of treatment.</p> |
| 申请公布号 |
JP2014159472(A) |
申请公布日期 |
2014.09.04 |
| 申请号 |
JP20140098831 |
申请日期 |
2014.05.12 |
| 申请人 |
WYETH LLC |
发明人 |
PICKAR JAMES HARRISON;KOMM BARRY SAMUEL |
| 分类号 |
A61K31/565;C07D401/12;A61K31/40;A61K31/403;A61K31/404;A61K31/435;A61K31/439;A61K31/4427;A61K31/443;A61K31/454;A61K31/496;A61K31/55;A61P5/00;A61P5/30;A61P9/00;A61P15/00;A61P15/08;A61P19/10;A61P43/00;C07D209/08;C07D209/10;C07D209/12;C07D405/04 |
主分类号 |
A61K31/565 |
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