| 摘要 |
PROBLEM TO BE SOLVED: To provide a novel compound having effects as an inhibitor of histone deacetylase (HDAC) and therefore exhibiting therapeutic usefulness.SOLUTION: There is provided a compound represented by the formula (I). (I), where X is C when ... is a double bond or X is N, CH or CQRwhen ... is a single bond, n is 1 to 10, R is H or QR, each R' is independently selected from H and QR, each Q is independently selected from a bond, CO, NH, S, SO, SOor O, each Ris independently selected from C1 to 10 alkyl, C2 to 10 alkenyl, C2 to 10 alkynyl, substituted or unsubstituted aryl or heteroaryl, acyl, C1 to 10 cycloalkyl, halogen, C1 to 10 alkylaryl or C1 to 10 heterocycloalkyl, L is nitrogen-containing heteroaryl and W is a zinc chelate residue. |
