发明名称 |
Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
摘要 |
<p>An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound or a pharmaceutically acceptable salt thereof, the compound being selected from the group consisting of
3-(3-(4-(pyridin-2-yloxymethyl)-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine;
3-(3-(4-(Pyridin-2-ylmethoxy)-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine;
3-(3-(4-pyridin-2-yloxymethyl)-benzyl)-isoxazol-5-yl)-pyridine-2,6-diamine;
3-(3-(6-benzyloxy-pyridin-3-ylmethyl)-isoxazol-5-yl)-pyridin-2,6-diamine; and
3-(1-(4-(pyridin-2-yloxymethyl)-benzyl)-1H-pyrazol-4-yl)-pyridin-2-ylamine.</p> |
申请公布号 |
EP2628738(B1) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20120193373 |
申请日期 |
2006.10.30 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
TANAKA, KEIGO;INOUE, SATOSHI;MURAI, NORIO;MATSUKURA, MASAYUKI;NAKAMOTO, KAZUTAKA;SHIROTORI, SHUJI;ABE, SHINYA |
分类号 |
C07D401/04;A61K31/4439;A61K31/444;A61P31/10;C07D401/14;C07D413/04;C07D413/14 |
主分类号 |
C07D401/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|