HIGH VISCOSITY TFF DEVICE DESIGN

摘要

A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.