| 发明名称 |
Compositions for inducing immune responses |
| 摘要 |
The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) at least first and second adjuvants, wherein the first adjuvant comprises microparticles and wherein the second adjuvant comprises an imidazoquinoline compound, and (c) a pharmaceutically acceptable excipient, which compositions elicits an immune response when administered to a vertebrate subject. The invention also provides methods of producing immunogenic compositions and methods for using immunogenic compositions (e.g., for treatment), among other benefits. |
| 申请公布号 |
US8815253(B2) |
申请公布日期 |
2014.08.26 |
| 申请号 |
US200812746723 |
申请日期 |
2008.12.04 |
| 申请人 |
Novartis AG |
发明人 |
Malyala Padma;O'Hagan Derek;Singh Manmohan |
| 分类号 |
A61K39/02;A61K49/00;A61K39/00;A61K31/437;A61K9/16;A61K39/07;A61K31/4745;A61K39/39 |
主分类号 |
A61K39/02 |
| 代理机构 |
|
代理人 |
Lee Helen;Bonham David |
| 主权项 |
1. An immunogenic composition comprising (a) a first antigen, (b) at least first and second adjuvants, wherein the first adjuvant comprises an organic microparticle and wherein the second adjuvant comprises an imidazoquinoline compound that is established within said microparticle, and (c) a pharmaceutically acceptable excipient, wherein said composition elicits an immune response against said first antigen when administered to a vertebrate subject. |
| 地址 |
Basel CH |
