| 发明名称 |
METHOD FOR MAKING A PRECURSOR OF L-FUCOSE FROM D-GLUCOSE |
| 摘要 |
A method that can be used to make a precursor of L-fucose from D-glucose that includes the steps of a) making a compound of formula (1) from D-glucose, formula (1) wherein R1 is acyloxy, and Q is a group (a), (b), (c) or (d), formula (a), (b), (c) or (d) or wherein R1 is OH, and Q is a group (e), (f) or (g); formula (e), (f) or (g) wherein R2 is acyloxy and R3 is a sulphonyl leaving group; and b) producing 6-deoxy-L-talose from the compound of formula (1) formed in step a), wherein the moiety is a highly lipophilic protecting group; compounds according to formula (1), and use of a compound according to formula (1) are provided. |
| 申请公布号 |
US2014235848(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201214348014 |
申请日期 |
2012.09.28 |
| 申请人 |
Glycom A/S |
发明人 |
BOUTET Julien;KHANZHIN Nikolay;BONACCORSI Filippo;DEKANY Gyula |
| 分类号 |
C07H9/02;C07H13/04;C07H11/00;C07H13/08 |
主分类号 |
C07H9/02 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method that can be used to make a precursor of L-fucose from D-glucose, that comprises the steps of:
a) making a compound of formula 1 from D-glucose, wherein R1 is acyloxy, and Q is a group (a), (b), (c) or (d), or wherein R1 is OH, and Q is a group (e), (f) or (g) wherein R2 is acyloxy and R3 is a sulphonyl leaving group; and b) producing 6-deoxy-L-talose from the compound of formula 1 formed in step a),wherein the moietyis a highly lipophilic protecting group. |
| 地址 |
Kgs. Lyngby DK |
