发明名称 |
Fusion protein of human fibroblast growth factor-21 and exendin-4 |
摘要 |
Provided is a fusion protein, which comprises human fibroblast growth factor 21 and glucagon-like-peptide-1 or its analogs. Also provided is the medicament composition comprising the fusion protein, which can be used for treating or preventing obesity, diabetes, hyperglycemia and hyperlipidemia etc. |
申请公布号 |
US8809499(B2) |
申请公布日期 |
2014.08.19 |
申请号 |
US201013391226 |
申请日期 |
2010.03.12 |
申请人 |
Chongqing Fagen Biomedical Inc. |
发明人 |
Fan Kai;Zhao Zhiquan;Zhang Chun;Chen Yong;Luo Hua;Yang Li;Liu Honghong |
分类号 |
C07K14/50;C12N1/21;C12N15/12;C12N15/63;C07K14/605;C07K14/43;A61K38/00 |
主分类号 |
C07K14/50 |
代理机构 |
Maschoff Brennan |
代理人 |
Maschoff Brennan |
主权项 |
1. A fusion protein having a formula of R2-R1 or R2-L-R1, wherein:
R1 is a human fibroblast growth factor 21; R2 is Exendin-4; and L is a linker. |
地址 |
Chongqing CN |