Hybrid referenceless and multibaseline PRF-shift magnetic resonance thermometry

摘要

Proton resonance frequency shift thermometry may be improved by combining multibaseline and referenceless thermometry.

主权项

1. A method of performing proton resonance frequency (PRF) shift thermometry, the method comprising the steps of:
acquiring multiple PRF baseline images of an imaging region, each baseline image corresponding to a PRF phase background; acquiring at least one PRF treatment image of the imaging region subsequent to a temperature change of a subregion within the imaging region; estimating at least one temperature-induced phase distribution of the imaging region based, at least in part, on (i) subtraction of a plurality of the baseline images from the at least one treatment image, and (ii) a smooth extension of at least one phase surrounding the subregion into the subregion; and estimating a temperature distribution within the subregion based on the at least one temperature-induced phase distribution.