发明名称 COMBINATORIAL LIBRARIES OF MONOMER DOMAINS
摘要 Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.
申请公布号 HK1144912(A1) 申请公布日期 2014.08.15
申请号 HK20100111574 申请日期 2010.12.13
申请人 AMGEN MOUNTAIN VIEW INC. 发明人 KOLKMAN, JOOST A;STEMMER, WILLEM P.C.
分类号 A61K;A61K47/42;A61K47/48;C07B61/00;C07H;C07K;C07K1/04;C07K14/705;C08F;C08F2/00;C12Q;C12Q1/68;C40B30/04;C40B40/10;G01N;G01N33/53;G01N33/543;G01N33/68 主分类号 A61K
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