发明名称 |
MASS SPECTROMETRIC DETERMINATION OF FATTY ACIDS |
摘要 |
The invention relates to the detection of fatty acids. In a particular aspect, the invention relates to methods for detecting very long chain fatty acids and branched chain fatty acids by mass spectrometry. |
申请公布号 |
US2014224976(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
US201414242075 |
申请日期 |
2014.04.01 |
申请人 |
QUEST DIAGNOSTICS INVESTMENTS INC |
发明人 |
GOLDMAN Scott |
分类号 |
H01J49/00;H01J49/42 |
主分类号 |
H01J49/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method for determining an amount of one or more very long chain fatty acids (VLCFA) and/or branched chain fatty acids (BCFA) in a sample by mass spectrometry, the method comprising:
(a) subjecting the sample to an ionization source to generate one or more VLCFA and/or BCFA ions detectable by mass spectrometry; (b) determining the amount of the one or more VLCFA and/or BCFA ions by mass spectrometry; and (c) relating the amount of the one or more VLCFA and/or BCFA ions determined in step (b) to the amount of the VLCFA and/or BCFA in the sample; wherein the VLCFA and/or BCFA are underivatized prior to ionization. |
地址 |
WILMINGTON DE US |