METHOD FOR THE SELECTION OF ANTIBODIES AGAINST BCMA

摘要

An antibody specifically binding to human BCMA, characterized in that the binding of said antibody is not reduced by APRIL and not reduced by BAFF, said antibody does not alter APRIL-dependent NF-&kgr;B activation, BAFF-dependent NF-&kgr;B activation, and does not alter NF-&kgr;B activation without BAFF and APRIL is useful as a therapeutic agent.