PROCESSES FOR PRODUCING HEXANEDIOL (HDO), HEXAMETHYLENEDIAMINE (HMD), ADIPONITRILE (ADN), ADIPAMIDE (ADM) AND DERIVATIVES THEREOF

摘要

Processes include producing hexanediol (HDO), hexamethylenediamine (HMD), adiponitrile (ADN), adipamide (ADM) and derivatives thereof from fermentation broths containing diammonium adipate (DAA), monoammonium adipate (MAA) and/or adipic acid (AA).

主权项

1. A process for producing nitrogen-containing compounds comprising:
(a) providing a clarified DAA-containing fermentation broth; (b) distilling the broth to form an overhead that comprises water and ammonia, and a liquid bottoms that comprises MAA, at least some DAA, and at least about 20 wt % water; (c) cooling and/or evaporating the bottoms, and optionally adding an antisolvent to the bottoms, to attain a temperature and composition sufficient to cause the bottoms to separate into a DAA-containing liquid portion and a MAA-containing solid portion that is substantially free of DAA; (d) separating the solid portion from the liquid portion; (e) recovering the solid portion; (f) contacting at least a part of the solid portion at least one hydrogenation catalyst to produce HDO; (g) aminating HDO to produce HMD; and (h) recovering the HMD.