发明名称 Indole and azaindole modulators of the alpha 7 nachr
摘要 This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I):; or a pharmaceutically acceptable salt thereof.
申请公布号 US8796283(B2) 申请公布日期 2014.08.05
申请号 US201013501418 申请日期 2010.10.14
申请人 Proximagen Limited 发明人 Dinnell Kevin;Lightfoot Andrew;Lunniss Gillian Elizabeth
分类号 A01N43/54;C07D239/42;C07D401/04 主分类号 A01N43/54
代理机构 Andrus Intellectual Property Law, LLP 代理人 Andrus Intellectual Property Law, LLP
主权项 1. A compound of formula (I):wherein: R1 is independently selected from the group consisting of H, C1-6alkyl, haloC1-6alkyl and halo; R2 is independently selected from the group consisting of C1-6alkyl, haloC1-6alkyl, halo, acetyl, cyano, CH2CN and cyclopropyl; and X is CH or N; or a pharmaceutically acceptable salt thereof.
地址 London GB