发明名称 |
Indole and azaindole modulators of the alpha 7 nachr |
摘要 |
This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I):;
or a pharmaceutically acceptable salt thereof. |
申请公布号 |
US8796283(B2) |
申请公布日期 |
2014.08.05 |
申请号 |
US201013501418 |
申请日期 |
2010.10.14 |
申请人 |
Proximagen Limited |
发明人 |
Dinnell Kevin;Lightfoot Andrew;Lunniss Gillian Elizabeth |
分类号 |
A01N43/54;C07D239/42;C07D401/04 |
主分类号 |
A01N43/54 |
代理机构 |
Andrus Intellectual Property Law, LLP |
代理人 |
Andrus Intellectual Property Law, LLP |
主权项 |
1. A compound of formula (I):wherein:
R1 is independently selected from the group consisting of H, C1-6alkyl, haloC1-6alkyl and halo; R2 is independently selected from the group consisting of C1-6alkyl, haloC1-6alkyl, halo, acetyl, cyano, CH2CN and cyclopropyl; and X is CH or N; or a pharmaceutically acceptable salt thereof. |
地址 |
London GB |