发明名称 AZETIDINE COMPOUNDS, COMPOSITIONS AND THEIR USE AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE
摘要 Provided are compounds of Formula I, R1-L1-A-L2-R2  (I), and stereoisomers, tautomers and pharmaceutically acceptable salts thereof, wherein A, L1, L2, R1 and R2 are defined herein. The present invention also provides a pharmaceutical composition and methods of using such compounds. The compounds are useful for therapy and/or prophylaxis in a patient, and in particular to inhibitors of Soluble Epoxide Hydrolase (sEH).
申请公布号 KR20140095515(A) 申请公布日期 2014.08.01
申请号 KR20147014180 申请日期 2012.10.29
申请人 F. HOFFMANN-LA ROCHE AG 发明人 CECCARELLI SIMONA M.;GUEROT CARINE;KNUST HENNER
分类号 C07D487/04;A61K31/397;A61P13/00;A61P15/00;C07D487/10 主分类号 C07D487/04
代理机构 代理人
主权项
地址