TRANS-ARTERIAL DRUG DELIVERY

摘要

It is provided herein methods, devices, and compositions for trans-arterial local delivery of therapeutic agent for the treatment of liver cancers.

主权项

1. A method of treating a liver cancer in a subject in need thereof comprising:
deploying a bioresorbable polymer scaffold in the lumen of a blood vessel that directly services a diseased liver or a cancer tissue therein, wherein the bioresorbable polymer scaffold comprises a polymer substrate and optionally a coating upon the substrate, wherein a first therapeutic agent is embedded or impregnated in the substrate, the coating if present, or both, wherein a therapeutically effective amount of the first therapeutic agent is released from the scaffold upon the deployment thereof over a period of time; wherein the first therapeutic agent is an anti-angiogenesis agent.