发明名称 Method for providing a dried reagent in a microfluidic system and microfluidic system
摘要 A method for providing a dried reagent in a microfluidic system is provided, the method comprising the following steps: providing a microfluidic system having a microfluidic structure, introducing a flowable carrier medium containing a reagent in the microfluidic structure, and drying the reagent in the microfluidic structure by lyophilization.
申请公布号 US8790932(B2) 申请公布日期 2014.07.29
申请号 US200912573472 申请日期 2009.10.05
申请人 Roche Diagnostics Operations, Inc. 发明人 Augstein Manfred;Roedl Romi;Wuerl Susanne;Winckler-Desprez Valerie
分类号 G01N1/42;B05D1/26;B01J19/00 主分类号 G01N1/42
代理机构 Dinsmore & Shohl LLP 代理人 Dinsmore & Shohl LLP
主权项 1. A method for providing a dried reagent in a microfluidic system, wherein the dried reagent is provided for a detection reaction with an analyte to be analyzed, the method comprising: providing a microfluidic system having a microfluidic structure, cooling the microfluidic structure, introducing a flowable carrier medium containing a reagent and at least one surfactant into the microfluidic structure, wherein the microfluidic structure is cooled before the flowable carrier medium is introduced therein such that the flowable carrier medium freezes upon introduction into and contact with the microfluidic structure, and drying the reagent in the flowable carrier medium in the microfluidic structure by lyophilization to provide the dried reagent for the detection reaction, wherein the reagent is dried by the lyophilization after the flowable carrier medium is frozen upon introduction into and contact with the microfluidic structure.
地址 Indianapolis IN US