发明名称 ACYLGUANIDINES FOR TREATING OSTEOARTHRITIS
摘要 The present invention relates to compounds of formula (I) and, in particular, drugs containing at least one compound of formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states, in the cause of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
申请公布号 WO2014111113(A1) 申请公布日期 2014.07.24
申请号 WO2013EP03794 申请日期 2013.12.16
申请人 MERCK PATENT GMBH 发明人 TSAKLAKIDIS, CHRSITOS;KLEIN, MARKUS;CZODROWSKI, PAUL
分类号 C07C279/20;A61K31/155;A61P5/28;A61P19/02;C07C279/22;C07C311/08;C07C311/16;C07C311/37;C07D233/61;C07D309/14;C07D317/58;C07D317/60;C07D333/20;C07D333/28;C07D335/02 主分类号 C07C279/20
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