Macrocyclic picolinamides as fungicides

摘要

The invention relates to macrocyclic picolinamides of Formula I and their use as fungicides.;

主权项

1. A compound of Formula I: wherein, R is H or C(O)R6; R1 is H, C(O)R6, or Q; Q is R2 is independently H, alkyl, alkenyl, aryl, heterocyclyl, each substituted with 0, 1 or multiple R5, or —C(O)R5; R3 is independently H, alkyl, or alkenyl, each substituted with 0, 1 or multiple R5; R4 is independently alkyl or alkoxy, substituted with 0, 1, or multiple R5; R5 is alkyl, alkenyl, halo, haloalkyl, alkoxy, haloalkoxy, C(O)R8, arylalkoxy, or aryl; R6 is alkoxy or benzyloxy; R7 is H, —C(O)R4, or —CH2OC(O)R4; and R8 is H, alkenyl, halo, haloalkyl, alkoxy, haloalkoxy, arylalkoxy, or aryl.