发明名称 Treatment of circadian rhythm disorders
摘要 Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception impaired patients, e.g., blind patients, and to methods of measuring circadian rhythm.
申请公布号 US8785492(B2) 申请公布日期 2014.07.22
申请号 US201313751011 申请日期 2013.01.25
申请人 Vanda Pharmaceuticals Inc. 发明人 Dressman Marlene Michelle;Feeney John Joseph;Licamele Louis William;Polymeropoulos Mihael H.
分类号 A61K31/343;A61K31/00;G01N33/68 主分类号 A61K31/343
代理机构 Hoffman Warnick LLC 代理人 Swinton, Jr. Stephen F.;Hoffman Warnick LLC
主权项 1. A method of entraining a patient suffering from Non-24 to a 24 hour sleep-wake cycle in which the patient awakens at or near a target wake time following a daily sleep period of approximately 7 to 9 hours, and maintaining said 24 hour sleep-wake cycle said method comprising: treating the patient by orally administering to the patient 20 mg of tasimelteon once daily before a target bedtime.
地址 Washington DC US