URIDINE PHOSPHORYLASE INHIBITOR

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a new derivative of uracil described by the following structural formula, and its pharmaceutically acceptable salt. The compound has the structural formula according to the R-enantiomer form:The given invention also refers to a method for preparing the above compound and to a pharmaceutical composition on the basis of the above compound. The method for preparing consists in a reaction of 5-fluoruracil and R-tert-butyl-3-iodopropane-1.2-diyldicarbamate.EFFECT: compound possesses the properties of uridine phosphorylase inhibitors and can be used as an active ingredient for preparing a drug for treating cancer, such as an antimetabolite of the uridine phosphorylase inhibitors of tumour cells.4 cl, 1 tbl, 1 ex