SYSTEMS AND METHODS FOR ANALYZING CODING SEQUENCES BASED ON GENETIC DISTANCES

摘要

Genetic distances between coding sequences of genomes are used to analyze sets of genomes. Genomic surveillance can be analyzed by identifying a proportion of coding sequences less than some filtration value from a closest ancestor, or by converting the coding sequences into a point cloud representation and using a persistence homology technique to find the zero-dimensional Betti number. A non¬ zero value of Betti numbers greater than zero can also indicate that nonvertical genetic exchanges have occurred.