| 发明名称 |
NOVEL SUBSTITUTED BICYCLIC TRIAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS |
| 摘要 |
<p>The present invention is concerned with novel substituted bicyclic triazole derivatives of Formula (I) wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p> |
| 申请公布号 |
EP2523955(B1) |
申请公布日期 |
2014.07.16 |
| 申请号 |
EP20110700171 |
申请日期 |
2011.01.12 |
| 申请人 |
JANSSEN PHARMACEUTICALS, INC.;CELLZOME LIMITED |
发明人 |
DE CLEYN, MICHEL, ANNA, JOZEF;VAN BRANDT, SVEN, FRANCISCUS, ANNA;GIJSEN, HENRICUS, JACOBUS, MARIA;BERTHELOT, DIDIER, JEAN-CLAUDE;OEHLRICH, DANIEL |
| 分类号 |
C07D471/04;A61K31/4196;A61P25/28;C07D487/04 |
主分类号 |
C07D471/04 |
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