BISPECIFIC BINDING MOLECULES FOR 5T4 AND CD3.

摘要

The present invention provides a bispecific binding molecule comprising a first and a second binding domain wherein the first binding domain is capable of binding to the epitope cluster 4 of T4 and the second binding domain is capable of binding to the CD3 receptor complex on T cells. Moreover, the invention providesa nucleic acid sequence encoding the bispecific binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention providesa process for the production of the bispecific binding molecule of the invention, a medical use of said bispecific binding molecule and a kit comprising said bispecific binding molecule.