| 发明名称 |
SYNTHESIS OF FR901464 AND ANALOGS WITH ANTITUMOR ACTIVITY |
| 摘要 |
<p>The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.</p> |
| 申请公布号 |
WO2014100367(A1) |
申请公布日期 |
2014.06.26 |
| 申请号 |
WO2013US76454 |
申请日期 |
2013.12.19 |
| 申请人 |
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
KOIDE, KAZUNORI;ALI OSMAN, SAMI, SAIF |
| 分类号 |
C07D493/10;A61K31/35;A61P35/00;C07D413/14 |
主分类号 |
C07D493/10 |
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