发明名称 |
ANGIOPOIETIN-2 SPECIFIC TIE2 RECEPTOR |
摘要 |
<p>In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoeitin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.</p> |
申请公布号 |
CA2895645(A1) |
申请公布日期 |
2014.06.26 |
申请号 |
CA20132895645 |
申请日期 |
2013.12.20 |
申请人 |
MEDICAL RESEARCH COUNCIL;UNIVERSITY OF LEICESTER |
发明人 |
BRINDLE, NICOLAS PHILLIP JAMES;SALE, JULIAN EDWARD |
分类号 |
C07K14/71;C12N9/12 |
主分类号 |
C07K14/71 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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