| 发明名称 |
Vault complexes for cytokine delivery |
| 摘要 |
The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer. |
| 申请公布号 |
AU2010313112(B2) |
申请公布日期 |
2014.06.26 |
| 申请号 |
AU20100313112 |
申请日期 |
2010.11.02 |
| 申请人 |
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ROME, LEONARD H.;KICKHOEFER, VALERIE A.;DUBINETT, STEVEN M.;SHARMA, SHERVEN;KAR, UPENDRA K. |
| 分类号 |
C07K19/00;A61K38/19;A61P35/00;C12N15/19;C12N15/62 |
主分类号 |
C07K19/00 |
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