摘要 |
<p>PROBLEM TO BE SOLVED: To provide tablets which disintegrate rapidly in the mouth, leave behind a pleasant sensation in the mouth, are mechanically very stable, and provide high content uniformity.SOLUTION: A pharmaceutical formulation in the form of agglomerates comprises the following components A) and B): A) an excipient consisting of a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of a disintegration agent, c) 1-15% by weight of water-insoluble, film-forming polymers, d) 0-15% by weight of water-soluble polymers, and e) 0-15% by weight of another pharmaceutically customary excipients, wherein the sum of the components a) to e) is 100% by weight; and B) at least one active ingredient.</p> |