发明名称 |
High Affinity Human Antibodies to Human Protease-Activated Receptor 2 |
摘要 |
The present invention provides antibodies that bind to protease-activated receptor-2 (PAR-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PAR-2. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more PAR-2 biological activities, including the treatment of pain conditions, inflammatory conditions and gastrointestinal conditions. |
申请公布号 |
US2014179903(A1) |
申请公布日期 |
2014.06.26 |
申请号 |
US201313850644 |
申请日期 |
2013.03.26 |
申请人 |
Regeneron Pharmaceuticals, Inc. |
发明人 |
MacDonald Lynn;Murphy Andrew J.;Papadopoulos Nicholas J.;Morra Marc R.;Salzler Robert R.;LaCroix-Fralish Michael L. |
分类号 |
A61K39/395;A61K45/06;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
US |