发明名称 ANTI-GDF15 ANTIBODIES
摘要 Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
申请公布号 WO2014100689(A1) 申请公布日期 2014.06.26
申请号 WO2013US77139 申请日期 2013.12.20
申请人 AVEO PHARMACEUTICALS, INC. 发明人 LERNER, LORENA;ABBOTT, SANDRA;BAI, AILIN;CHEN, TING;CHIU, MARIA, ISABEL;LIU, QING;POLING, LAURA;TAO, NIANJUN;WEILER, SOLLY;WENG, ZHIGANG;WINSTON, WILLIAM, M.;GYURIS, JENO
分类号 A61K39/395;A61P35/00;C07K16/22 主分类号 A61K39/395
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