N- (4 -QUINOLINYLMETHYL) SULFONAMIDE DERIVATIVES AND THEIR USE AS ANTHELMINTICS.

摘要

Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein (1), Q, A, R1, R2, R3 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for treating helminth infections comprising administration to an animal a parasiticidally effective amount of a compound or a composition of the invention. Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein (1), Q, A, R1, R2, R3 and n are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for treating helminth infections comprising administration to an animal a parasiticidally effective amount of a compound or a composition of the invention. The techniques herein relate to a probe for forming a seal between a downhole tool and a wall of a wellbore. The probe includes a probe inlet extending from the downhole tool for fluid communication with a subterranean formation, a base positionable about the downhole tool about the probe inlet, a packer positionable on the base for forming a seal with the wellbore wall, and a raised packer support and/or packer stopper for supporting the packer as the packer is compressed against the wellbore wall. The packer may have an inlet channel extending therethrough for receiving the probe inlet. The raised packer support can extend from the base for supporting the packer, and the packer may have a support channel extending a distance therein for receiving the raised packer support. The packer stopper can extend from the base about a perimeter of the packer with an expansion gap defined therebetween.