发明名称 |
BACE INHIBITORS OF IMINOTHIADIAZINE DIOXIDES |
摘要 |
In its many embodiments, the present invention provides certain C2-ring-substituted iminothiadiazine compounds, or a tautomers thereof, and pharmaceutically acceptable salts of said compounds and said tautomers. The novel compounds of the invention are as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed. |
申请公布号 |
WO2014093190(A1) |
申请公布日期 |
2014.06.19 |
申请号 |
WO2013US73781 |
申请日期 |
2013.12.09 |
申请人 |
MERCK SHARP & DOHME CORP.;CUMMING, JARED, N.;SCOTT, JACK, D.;BIFTU, TESFAYE |
发明人 |
CUMMING, JARED, N.;SCOTT, JACK, D.;BIFTU, TESFAYE |
分类号 |
A61K31/549;A61P25/28;C07D285/18 |
主分类号 |
A61K31/549 |
代理机构 |
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