发明名称 USES OF MONOCLONAL ANTIBODY 8H9
摘要 This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides a method of inhibiting the growth of tumor cells comprising contacting said tumor cells with an appropriate amount of monoclonal antibody 8H9 or a derivative thereof.
申请公布号 US2014161814(A1) 申请公布日期 2014.06.12
申请号 US201313958902 申请日期 2013.08.05
申请人 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 发明人 CHEUNG Nai-Kong V.
分类号 C07K16/30 主分类号 C07K16/30
代理机构 代理人
主权项 1. An antibody secreted by hybridoma 8H9.
地址 New York NY US